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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f646e7d438358a1b7f2edb44dba707f7d14d66a7f3e3ed1b8278deb047f1b6f' 
  AND token = 'CdO4WPdnP5CT31mCT3EN7sal0LwlDl/bRL5sC6AaZKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}