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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38fe03da6e5fe1d77005024e4e35785e62a7d0b0b88f95e3e47d388a4cda4653' 
  AND token = 'cV0sMwviHBnhmzggRDT4h5q1lTl5CQNEk9aIhJbnzHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}