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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f9245a52de143b37da364cc7fbc35b5cd2683fc907437f25a390c37bd5bce59' 
  AND token = 'oVvzbe8Kz5d+qeIbYRISdi1zYA9azPnl/Vbt2JCpQ44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}