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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105916d0499fe28ca7ab4daa415d0df318ba3628e253a33a0c98065a3e38bdee' 
  AND token = 'QilCi71r2dNgEDW4sLzBMb+uaoZ3/CPAVcfRB6kYuxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}