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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24cfd18fbd74c116058e153415d2a2b44e25154234368de23499fa7a546a2921' 
  AND token = 'ez6cq7RMKy/S/KJKlzYhH47FWF1aN8/BNmrcj/Ighns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}