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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd129ab1efb57f4f55e6124310b4b73078be887c9f7690019e1501ed401ec1e8a' 
  AND token = 'JGdHI4a+taPLlP8Xyq7xLJGLvaVfMYRwuRCHoIS+Lq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}