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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c22ce0b85ceddb8929526ce7ebab78444ec03423e9e5c33f362066779af3c1fa' 
  AND token = 'b/T0l2nY+/i8t6vhYMDQSvH52XB0W/0nncPSDzjThKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}