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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b5b89c2f504c5e210db0cf8f454ab2daf468fa15988ec6ddb88eef1a0a6893' 
  AND token = 'uy9bElVrbdBq2wqDwfdO1oIW1psKK6a0KfY0lUID6mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}