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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00fded719173bb78dab496e3c5b69ba053ed03f5753dac496536ba3b4ca025c7' 
  AND token = 'IaO3MwjE+CUfF7rdXm5Zjh6hKxNRhcOeaW5QB1+g6Ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}