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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3e1043a0a849da205dd0520108dc219ea97e75ec405c2cca3389a9c35d5dfa' 
  AND token = 'FEI6c1iAGPfQCMGzrT8vj7MGbzaeoGns4YOxrEgN9k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}