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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eee846edbff178b76e36c43cf8418b0ee27a0c98a097554426d94b014146eb3f' 
  AND token = 'O8OcO5pg7XEfLNXhom4PQtRR0y1JpF691I7uPqSM7og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}