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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da7ec148364d43bb63b37bb4100a998eb85b3d39e1bdc3b8544aeb1bbe1a350a' 
  AND token = 'Vb2ZJbYEK4Ru/01i5aFoHKQCQVMa354GbAADgJ5mrME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}