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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458a3ad7aa1100816ed682124e2965c03ce318a4eb70abeced164db3ad2739a1' 
  AND token = 'NPBWOmiX0c1Mhp+JID2I/mF/Egs14DVegOQTdW4bcSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}