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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20c3556eb5c7728a1e7afd579ae424e9de1e584ec33b0cedefc2ca614f2dda64' 
  AND token = 'LUd+sODont5YSLnkJ65UO/K9DwvTNz9fu1KjwfNKdo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}