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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341257e977f9ddb928c1d13d37defe44ea7800a734529fadb8a19ff7c01f7ad2' 
  AND token = 'eDZPhmsgsZwywwmJQfNIwkn0j9Cj1H8q41qobA4xwYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}