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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2800aa0459e5c00395ee40d0f5b3e12d143efb80c8ab433222ad140f2e09ae13' 
  AND token = '2x8r1bj8+tKVQw0AMdnWnGue675XoLb4TNnoAXR8LDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}