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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ef71b1e3e7b4dbec149871c5b9b2cc2a5d162a672beca057d4e60bd43ada32' 
  AND token = 'pp9UCDqfi0mTYpFXmxysvIotPsEtd49BzxretwQgZj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}