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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e9e66fdc320b1d0b9d2b63416175917ad30eaaf23cbf6685f0394cd8849e71c' 
  AND token = 'LYpGPz2sKxEzcwMK3IlHgy0XEm1WL02SwtqSG06Cu/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}