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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d3016ffe84372d76775b31644acb2734d7c63d536766f3c2eff10a32727b424' 
  AND token = 'iHw1tV8tjElP8Mxaz/4l3ujrf/mjjrihzvfnxgBAb0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}