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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d01ebb666ce86719250daa40b3121682229b9e0189333bb0f1389b81fb7708f' 
  AND token = 'ksIfJ559Coi/ly9WFzUwXcEVq0f51w4rl1FG7SAP2eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}