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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1caf61485a2f50470db6ccd5c06e5421183b102a8bfff0220d5d88bd548ffe00' 
  AND token = 'VkBxydd2tkvEdx9XFccrWN+Qet573rCy4B0BvyIjywA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}