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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd880a8e0cefb32e59ea58478bea4616ddaba242e4e431845b5e17e2abb09ce95' 
  AND token = 'If1rnzNBGk3qYeYNh2eYj/sdM3I8InUo/WU6GJZIM68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}