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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2402e357bf56fcb774dd92a4041d6bdecc49aeecb77dca9ccfc6448a4538bc56' 
  AND token = 'RB3AzT6j6b3q/JPSVHbGVkUay23v36mCgy5vZ19x9js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}