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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb6a57f7e56c0e564f70c95184ac22f9b8c19f0d738639322b4bd245bbcbe06' 
  AND token = 'zwBxMY44pJoeTy4f0FgrvteTC9nPHr/FKs7HNTqa3BY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}