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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f316b5593c5384d5ab63369c8622bfdc6019db51298c66a7c246322809a6abd3' 
  AND token = 'hYVKX3TzDOanigB2sz4bP+ubD8qcEiG8a51TP74cBBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}