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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665a863040d1c45fa8a63d8e7c9a764c0cf7e184eb222becbad354bfd68b5d3b' 
  AND token = '15EZhaXID6rpFpH2V8kOB6K3YU4OmmzwLNXF+tHqTys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}