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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4829f5cb7db399f131e9c4626e9b8db998c7fb1f64b23611493a201d314ec1c5' 
  AND token = 'rRbevStMw3o1SUK+B3yHp1zaYAVJQFUeyD/gPleu+6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}