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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3b5cb24c4ba08c6c9d09bec6a10eb1aeccb89800f7d1c6b667702052e09595b' 
  AND token = 'ZPKB7v/t39k1dDXrAhVfZpvXdkZ2T38w2gh8BXYw8TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}