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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d5e8ef3f0f5a12bcbe68b1ef91b2dd1641515c7d39ba1cbf961276994457f67' 
  AND token = 'mBWE7gLFlHRo3NtBvOkd4vMrd9ZA+b7T8UmtQRQSVZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}