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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '523f6c1c5020102a2270c7161b2b3957be2d36a8c052b2dc54451df94e9a23c0' 
  AND token = 'nCApdpN01moCpf5KyrphMtvM5OLxH9uYIQ4gis4pYtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}