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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c7f9d17cbb0375b5d68f55638f84e81378c34ae223e8aeaa1dedae073cf5b4f' 
  AND token = 'm+L6VaEqRxKewCSNPqcu4x8qpnxW7Uh1V/t+ItUCOrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}