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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4d3c5df46a948bc93eaa40ce10ec2fd5fdc73beb19e2cd24ef22030d0e8a117' 
  AND token = 'GvEKY8ie5htAGhgnVt3Jg385MXgPBHs2Ao8Z6L56jJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}