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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '978dac7eaa524f34e0a35f3a0fc8580a120f22d52a5dbced20b60675b7a60b41' 
  AND token = 'U5nyHyWzYoe+eptiOPeI3egLqhTwlYiO9bI9tnxudnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}