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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d0a05d32043fe4b99cc0512a1c99ee4bb1dd605f15146eb6c31f630b104a2df' 
  AND token = 'AVBvVWjCwT0uNxHWwKmiaCvo8/TC/biZcY+b8ZMOaRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}