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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79ebc281cac40cf94acdca0f5f015bf0e4ae72c8c714aa8ed0db49f10fd3e972' 
  AND token = '64OZSSZQXbR2COM7x3N99ukm1HfDtk86U/e++pO0NdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}