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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e8305701ee11e022e1f49a6fb561ca30defa1b77ee41244bdee3b9166c5f1a' 
  AND token = '785Dn3iRqqMaz/Oh6PcV6bsfrklAElkWrirD6+nPSgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}