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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4cf166dc5826e33f07461d2112d366460cc84cd161e0469e7f9c206e6a7b679' 
  AND token = 'm7uZE7nqNaPjP2/mk1DJ8j4PTzwZkA9bNdynNsNJuDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}