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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8541a36167c61851e088f436b36a8895d297f63d55328158280512ded63a1100' 
  AND token = '1T7o4RiKh6ayBowSp3wdz7KRLADnC0b6Rlcbyx8C7ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}