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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78942d7d1c2887afd164927d1c06e06791c437151289158a87f02c40fcab649' 
  AND token = '9/fTUb4xb3IfRjWdN4z5SDL8/Sxh+7zSV2diSEhb/I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}