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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b6425962d7bef8fd9a809cb7166e98ffa70cca9f452641f4d86f79b28ff1110' 
  AND token = 'tmeWxBMrIoo5sSI/q2OPtgyniilQw3z2ZA7TEGyL4b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}