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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a05ace0cfe17292d1f77961aff50995f9fb2935c775e8272cc01377aaf75ae4c' 
  AND token = '7/Tg5aBTKW0BTYHkCLlLTKbWMf4LZ9fC6pT7RpQi/hE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}