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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adf5d75b00b17f126300f13001691964d00525bc455b4565dc1dd4f5ffd457b3' 
  AND token = 'U5IC1GHe3zpN+Q/M1rXZSA/ZGXqHVywrT8B+lbRamgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}