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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a23cf40ef01a19da826742a7a64e37a6eadb0504de3e8ad32c067b12ffdc64' 
  AND token = 'XveDCmUEW/N1iU7Zyhaiq/r2x7LjtlWzrU2bHrLqkk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}