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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4332671d4bc5ada45b98d09750b1f30b8dafec8973988fbc8c6a0f93bf572385' 
  AND token = 'Y8FN5vyyG5vYle1y2/riSoeK6tjgxfkOKOn15fByndE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}