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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f420b0c7985f6a6011aa191d20b43188f769b5e150e69fef2eb376ceac81fce' 
  AND token = 'gEJKzIpJ0IG2k4DSv/c+wW5ioCZ97gOW7b4czuJUtt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}