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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b2e94ff62fc1f8fd14f3abbb2f67d55d3c8167fa9816d86e2d92655db5a652' 
  AND token = 'g2gOagH6nlWqcdgc4vZH8RhLnaTOAxdrwYEmV/OCfTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}