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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eacf9a457cf9456318b45b086854c8d05a27018302f3c099e29ea988c0cdfd5' 
  AND token = 'XU5BirIz/QkN7bTdPiDfsdk/tVCZj5Of9hhZtS40JFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}