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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '852a584bfcf6630bd44b37b30f2faf49a22563a382989f0dee729450acb9860d' 
  AND token = 'k6lAxLeHhA7NoSgJZQkE8URIEd0uG7kWlJLeFyjQBoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}