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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c634c742280139100eba804acab38854c1b184dcebd3e2475edc0c78f6a48fd8' 
  AND token = 'gx3rLsm47n7CDehrabzq/0BvwVqNj1Sb8d21kgH0Xec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}