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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '116a05238ff6463d11243b318e450e28dd9089de880fbcdb7030a1b1bf7ec15f' 
  AND token = 'X6mBVEx4yVAr64IwZO+GunBbq49VdLMbsn66GqdFmmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}